Innateimmunity相关论文
Assessment of humoral immunity and nutritionally essential trace elements in steady-state sickle cel
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Ectopic Expression of TRIM25 Restores RIG-I Expression and IFN Production Reduced by Multiple Entero
Enteroviruses (EVs) 3C proteins suppress type Ⅰ interferon (IFN) responses mediated by retinoid acid-inducible gene Ⅰ(......
Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouse γδ T c
The distinct characteristics of γδ T cells determine their vital roles in the formation of local immune responses and ......
Cytosolic nucleic acid sensors are critical for sensing nucleic acids and initiating innate immunity during microbial in......
Developmental Temporal Patterns and Molecular Network Features in the Transcriptome of Rat Spinal Co
The molecular network features of spinal cord development that are integral to tissue engineering remain poorly understo......
The cyclic GMP-AMP (cGAMP) synthase (cGAS) has been identified as a cytosolic double stranded DNA sensor that plays a pi......
维甲酸诱导基因-I编码抗病毒先天免疫应答中重要的细胞内模式识别受体,其识别病毒RNA后,启动抗病毒信号通路,诱导干扰素和促炎细胞因......
Type Ⅲ interferons (IFNs) represent the most recently discovered group of IFNs.Together with type Ⅰ IFNs (e.g.IFN-α/......
Diverse transcriptional patterns of homoeologous recombinant transcripts in triploid fish (Cyprinida
Homoeologous recombination (HR),the exchange of homoeologous chromosomes,contributes to subgenome adaptation to diverse ......
Single-cell mass cytometry (SCMC) combines features of traditional flow cytometry (i.e.,fluorescence-activated cell sort......
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Assessing interference of nanoparticles with the inflammatory response by a novel in vitro model bas
Engineered nanoparticles, even in the absence of toxicity, may interfere with the normal development of the innate/infla......
Interleukin receptor-associated kinase (IRAK)-1 binding protein 1(IRAK1BP1) is a critical factor in preventing dangerous......
Single CRD containing lectins from Macrobrachium rosenbergii (MrLec and MrCTL) participate in innate
C-type lectins (CTLs) play important roles in the innate immunity of invertebrates.Although several reports showed that ......
Pathogenicity of duck plague and innate immune responses of the Cherry Valley ducks to duck plague v
Duck plague caused by duck plague virus (DPV) is an acute and contagious disease.To better understand the pathogenic mec......
Dietary administration of Bacillus subtilis HAINUP40 enhances growth, digestive enzyme activities, i
The probiotic properties of Bacillus subtilis HAINUP40 isolated from the aquatic environment, and the effects of dietary......
The Receptor Kinase XAK1 Regulates the Early Signaling of the Pattern-recognition Receptor XA21-medi
Plants sense potential microbial invaders by using pattern-recognition receptors to recognize pathogen-associated molecu......
Molecular cloning and response to bacteria infection of arginine kinase in the mud crab,Scylla param
Arginine kinase (AK) was previously reported as a phosphagen-ATP phosphotransferase found in invertebrate.In this study,......
With the extensive development and application of rare earth element(REEs),the content of REEs in some foods exceeds the......
C-type lectins (CTLs) play important roles in invertebrate innate immunity by recognizing and eliminating pathogens.This......
Identification and molecular characterization of a peritrophin-like gene,involved in the antibacteri
Peritrophin was first isolated from insect peritrophic membrane(PM)and was thought to protect insects from invasion of m......
A putative PPR gene Esl1 is essential for plant active growth and negatively regulates innate immuni
Maintaining active growth and effective immune responses pathogens is crucial for a living organism to survive.In rice, ......
Catfish hepcidin gene is expressed in a wide range of tissues and exhibits tissue-specific upregulat
Antimicrobial peptides (AMPs) are important components of the host innate immuneresponse against microbial invasion. ......
Rice is a staple food and accounts for 16.2% of daily food intake in Japan.Rice is the third protein source,which follow......
Dicer is an key initiative protein of the RNA interference (RNAi) pathway that play an important role in shrimp viruses ......
Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through
Epigenetic regulation of type I interferon (IFN) production in the antiviral innate immune response remains to be fully ......
Zinc finger protein DPZF promotes TLR-triggered innate immunity by repressing IkBa gene transcriptio
Background: The ability of the innate immune system to recognize and eliminate invading microbial pathogens has been lar......
Phosphatase PP4 negatively regulates antiviral innate immune response by dephosphorylating TBK1 in m
Effective recognition of viral infections and subsequent production of type Ⅰ interferon are essential for the host ant......
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Dectin-1agonist curdlan modulates innate immunity to Aspergillus fumigatus in human corneal epitheli
AIM To explore the immunomodulatory effects of curdlan on innate immune responses against Aspergillus fumigatus(A.fumiga......
Critical role of autophagy as innate immunity against bacterial infection for enhancing bacterial cl
Our laboratory has focused on dissecting the role of (macro)autophagy in Gram-negative bacterial infection....
In vitro and in vivo antiviral activities of matrix metalloproteinase 3 in a vesicular stomatitis vi
Objectire: Vesicular stomatitis virus (Barber) is a single negative-stranded RNA virus that infects domestic and wild ma......
We recently reported that nucleotidebinding oligomerization domain (NOD)2, an important cytoplasmic pattern recognition ......
MDA-5 is an important pattern-recognition receptor in the innate immune system,capable of sensing viral RNA and activati......
Identification of Type Ⅰ IFN in Chinese giant salamander (Andrias davidianus) and the response to an
The type Ⅰ IFNs play a major role in the first line of defense against virus infections.In this study,the type Ⅰ IFN g......
Purpose To investigate the expression and function of Mannose Receptor(MR)and explore its interaction with Dectin-1 in h......
NPR-9 Regulates Innate Immunity by Antagonizing Functions of AIB Interneurons in Caenorhabditis eleg
Background: In human beings, mutations of GRPR gene are associated with the occurrence of several diseases, such as auti......
An Essential Role for the NLRP3 Inflammasome in Host Defense against Cryptococcus neoformans infecti
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Being a first-line defense, the epidermis is in constant confrontation against pathological or mechanical insults that d......
Small GTPase genes in Yesso scallop (Patinopecten yessoensis) and the up-regulation of Rho GTPase ge
Small GTP-binding proteins, also known as small GTPases, regulate diverse processes in eukaryotic cells such as signal t......
TRIM26 negatively regulates interferon-β production through polyubiquitination and degradation of nu
Virus infection leads to the activation of transcription factor IRF3 and subsequent production of type Ⅰ inteferons, wh......
Background: Innate immune defences to CSFV infection are triggered through the recognition of the host germline-encoded ......
Previous studies in our laboratory show that Spodoptera litura innexin2 and innexin3 are conserved, expressed and formed......
Maintaining active growth and effective immune responses pathogens is crucial for a living organism to survive.In rice, ......
Objective During human innate immunity response,PKR (Protein Kinase R) regulates host antiviral and anti-microbial activ......
Immune recognition of pathogen-associated molecular patterns(PAMPs)by pattern recognition receptors often activates proi......
Genome-wide Characterization and Expression Profiling of Immune Genes in the Diamondback Moth,Plutel
The diamondback moth,Plutella xylostella(L.),is a destructive pest that attacks cruciferous crops worldwide....
Cloning and Functional Analysis of the Serpin Genes Involved in Melanization in the Diamondback Moth
Serpins,which functions primarily on the inhibition of serine proteases,can regulate a prominent innate immune response ......
Syntenin is a multifunctional cytosolic adaptor protein that contributes to cell migration,proliferation,attachment,and ......
As lack of acquired immunity,innate immunity has played a very important role in insect....